Giuliana Medrano

Dr. Giuliana MedranoMedrano 

Contact Information

Phone: 870.680.4361   
E-mail: gmedrano@astate.edu

Biography
Research Assistant Professor (current)

Post Doc - Arkansas State University, ABI, Jonesboro, AR

PhD - Biochemistry and Molecular Biology, Cayetano Heredia Peruvian University, Lima, Peru

MS - Microbiology, Federico Villarreal National University, Lima, Peru

DMV - Doctor of Veterinary Medicine, San Marcos National University, Lima, Peru

BS - Veterinary Medicine, San Marcos National University, Lima, Peru

Research Focus Areas
Plant-made pharmaceuticals and vaccines

Bioproduction of interleukin-12 in transient plant-based platform

Enhancing recombinant protein expression by using antioxidants

Effects of nicotine in the gene expression of mouse neuroreceptors

Selected Peer-review publication
Medrano, G., Stephens, N., McMickle, A., Dolan, M.C., Erf, G., and Cramer, C.L. 2010. Efficient plant-based production of chicken IL-12 yields a strong immunostimulatory cytokine J. Interferon Cytokine Res. 30:143-54.

Liu, C., Towler, M.J., Medrano, G., Cramer, C.L., Weathers, P.J. 2009. Production of mouse interleukin-12 is greater in tobacco hairy roots grown in a mist reactor than in an airlift reactor. Biotechnology and Bioengineering 102:1074-1086.

Medrano, G., Reidy, M.J., Liu, J., Ayala, J., Dolan, M.C., and Cramer, C.L. 2009. Rapid system for evaluating bioproduction capacity of complex pharmaceutical proteins in plants. In: “Recombinant Proteins from plants”, Methods and Protocols. Series: Methods in Molecular Biology. L. Faye, and V. Gomord, eds. Humana Press, Totowa, NJ, vol 483:51-67.

Condori J., Medrano, G., Sivakumar, G., Nair, V., Cramer, C.L., and Medina-Bolivar, F. 2009. Functional characterization of a stilbene synthase gene using a transient expression system in planta. Plant Cell Rep.28:589-599.

Solis, J., Medrano, G., and Ghislain, M. 2007. Inhibitory effect of a defensin gene from the Andean crop maca (Lepidium meyenii) against Phytophthora infestans. J. Plant Physiol. 164:1071-1082.

Cuellar, W., Gaudin, A., Solórzano, D., Casas, A., Nopo, L., Prakash, Ch., Medrano, G., Kreuze, J. and Ghislain, M. 2006. Self-excision of the antibiotic resistance gene nptII using a heat inducible Cre-loxP system from transgenic potato. Plant Molecular Biology Journal 62:71-82.

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